I just ran a very simple tool that comes in Windows, the Magnifier. But it immediately crashed my Vista Ultimate installation with a Blue Screen of Death (Stop Error). It said something about Video Memory Manager Error. Just before the crash, Vista tried to switch to Basic skin, possibly 16-bit mode. Anyway it's strange that such a simple accessory that comes preinstalled with Windows caused such a serious error. Could be my video card? Let's see what Microsoft has to say about this.
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